There’s an invisible world on your skin —
an ecosystem of microbes that,
when balanced, keeps your skin
hydrated, youthful, and radiant
LIVING SKINCARE FOR LIVING SKIN
so we created:
THE NEXT EVOLUTION OF PROBIOTICS FOR SKIN HEALTH
Feel the beauty of a balanced biome
THE PROBIOTIC SERUM
$35*
30 ampoules / 1.35 fl oz total
Live probiotic serum designed to restore your skin’s microbiome.
A Complete Live Microbiome Activation System that has everything your skin biome needs to rebalance from the root
Our biome-balancing serum for overnight biome restoration and reshaping. Our silky formula is crafted with live probiotics that produce postbiotic metabolites that improve hydration, reduce TEWL (transepidermal water loss), and calm inflammatory pathways in the skin.
Each ampoule contains enough serum for a generous amount on the face, neck, and décolletage
You’ll wake up to:
A hydrated, healthy glow
Calmer skin with less redness
Fewer flare-ups of breakouts or irritation
A stronger skin barrier that resists dryness & damage
Long-term resilience and balance
*Beta testers pay $45 + shipping now and receive a $10 rebate upon completion of the feedback form.
BIOME. BARRIER. BALANCE. BIOLOGY
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Lactobacillus plantarum
A live probiotic strain that helps rebalance the microbiome, supports barrier function, and produces metabolites that hydrate, protect, and calm skin from within.
Snow Mushroom (Tremella fuciformis)
Known as “nature’s hyaluronic acid,” this mushroom holds up to 500 times its weight in water for deep hydration. It also contains polysaccharides that act as prebiotics, feeding your skin’s beneficial microbes.
Spirulina
A nutrient-dense blue-green algae packed with proteins, vitamins, and antioxidants. It helps protect against oxidative stress, supports skin regeneration, and provides amino acids that benefit both your skin cells and its microbiome.
Green Tea Extract
A powerful natural antioxidant that helps defend against environmental stressors, reduce visible redness, and support overall skin balance. Rich in polyphenols for calming and protecting the skin.
Beta-Glucan
A natural prebiotic from yeast that nourishes good bacteria and helps them adhere to the skin’s surface. It also soothes irritation and supports repair for a calm, resilient barrier.
Trehalose
Extracted from seaweed, trehalose is plant-derived sugar that acts as food for beneficial bacteria, helping them thrive. It also protects skin cells from dehydration and oxidative stress, keeping your microbiome healthy and active.
Ceramide NP
A skin-identical lipid that locks in moisture, reinforces the skin barrier, and prevents water loss. Ours is derived from plant sources to restore hydration and barrier strength naturally.
Oat Extract Powder
This extract calms visible redness, soothes sensitivity, and helps maintain hydration—all while supporting a healthy environment for good bacteria.
Inulin
A plant-derived prebiotic fiber (from chicory root) that feeds beneficial bacteria, helping them colonize and outcompete harmful microbes for a healthier skin ecosystem.
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Directions: Because live bacteria are not shelf stable when hydrated, the serum comes in single-use ampoules. Use every day to every three days for maximum benefits. Each ampoule contains enough serum for a generous amount on the face, neck, and décolletage.
Routine: Use at night by itself. Since live bacteria are high-maintenance princesses, the Probiotic Serum should be used separately from other skincare. If using other actives, alternate nights using the Probiotic Serum and using your other skincare.
Storage: Store in a cool dry place. Keep bag sealed when not in use. Do not leave it in a hot and humid place for an extended period of time.
Warning: For external use only. Avoid contact with eyes. Do not use on broken skin. Do not use if you are allergic to any ingredient. Discontinue use if irritation occurs. Keep out of reach of children.
SCIENCE-DRIVEN, BIOME-FIRST SKINCARE
Skincare guided by the latest clinical research in skin health, not marketing fads.
Unlike most “probiotic” skincare that uses postbiotics, ferments, or bacterial lysates, we use true live probiotics—delivered fresh to your skin’s ecosystem.
The Probiotic Serum is a
Complete Live Microbiome Activation System:
✓ Formulated with living probiotics to restore microbial balance
✓ Prebiotics to feed them
✓ Supportive nutrients to help them thrive
✓ Functional botanicals to calm, hydrate, and protect
✓ Minimal, clean ingredients that won’t disrupt your skin
✓ Based on holobiont biology, treating skin and microbes as one ecosystem
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"My face tends to get extremely dry to the point where putting on foundation is embarrassing because it just highlights all the little cracks and flakes. But after a few days of using the Probiotic Serum, my skin was noticeably less dry! I can actually use foundation some days now without it making me look more dry!"
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"I've had a really stubborn rash for the last few years that I have tried literally everything for and nothing has helped. It's been so annoying because it's constantly itchy and uncomfortable. After using the Probiotic Serum just one time I noticed a big difference! My skin was so much more calm. I'm really excited to keep using it"
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"My skin is insanely sensitive. I don’t even use “gentle” makeup remover wipes because they always burn! But I used the Probiotic Serum and had no reaction or stinging and I didn’t even need my tallow after! This is a game changer for my skin"
BETA TESTING PROGRAM
Be one of the first 100. Lead the Revolution..
Order now to save $$$ + give feedback for a $10 rebate
We’re releasing our probiotic serum to a small group of early adopters who believe there’s a better way to care for their skin.Each ampoule contains enough serum for a generous amount on the face, neck, and décolletage
This is not our official launch. We’re releasing only 100 bags of our first formulation at a special low price in exchange for honest feedback. Your experience will directly shape the final product.
Our beta testers will...
Receive the first formulation of our live probiotic serum
Be part of shaping the future of skincare through your feedback
Try the serum for the lowest ever cost that it will ever be
Get a $10 rebate when you fill out the feedback form
Join us in redefining skincare from symptom-fighting to true skin health.
Why do we use live bacteria?
Just like your gut, your skin has a microbiome that protects, repairs, and balances when it’s healthy.
The good bacteria on your skin:
CALM & HYDRATE
Good bacteria create postbiotics like lactic acid, short-chain fatty acids, and bioactive peptides to hydrate, calm inflammation, and support smooth, even skin
DEFEND & PROTECT
Good bacteria produce antimicrobial peptides and barrier-strengthening compounds
STRENGTHEN
They signal skin cells to reinforce the barrier and train your immune system to respond appropriately instead of overreacting
Adding live beneficial bacteria reprograms your skin’s ecosystem — allowing it to protect, repair, and regenerate naturally.
DOCTOR FOUNDED
WELLNESS GIRLIE APPROVED
Dr. Caitlyn Kellogg, Dermatology resident at Harbor-UCLA and UCSD School of Medicine graduate, has been captivated by the science of dermatology since middle school. She’s dedicated her career to helping patients overcome frustrating and painful skin conditions, finding deep fulfillment in restoring both health and confidence. At the forefront of emerging skin science, she brings her clinical expertise and passion for healing to co-founding SymbiōSkin.
A MIT grad, holistic wellness coach, and former victim of "untreatable" skin issues, Marisa Maas is a lifelong science nerd with a passion for helping people work with their bodies instead of against them. After years of suffering from stubborn skin issues and seeing the limits of conventional approaches, she turned her pain into a mission—merging cutting-edge research with a deep respect for the body’s natural ecosystems—and co-founded SymbiōSkin.
Two very different backgrounds. One shared passion for true skin health.
SymbiōSkin combines clinical science with holistic wellness for the best of both worlds:
→ clinically backed, science-driven, and doctor-approved
→ natural, nontoxic, and holistic.